O'nyong'nyong virus

O'nyong'nyong virus
O’nyong’nyong virus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Togaviridae
Genus: Alphavirus
Species: O’nyong’nyong virus
O'nyong'nyong virus
Classification and external resources
ICD-9 066.3

The O'nyong'nyong virus or O'nyong-nyong virus is a virus[1] first isolated by the Uganda Virus Research Institute in Entebbe, Uganda in 1959. It is a togavirus (family Togaviridae), genus Alphavirus and is closely related to the Chikungunya and Igbo Ora viruses. The name comes from the Nilotic language of Uganda and Sudan and means “weakening of the joints". The virus can infect humans and may cause disease.

Contents

Transmission

O'nyong'nyong virus is transmitted by bites from an infected mosquito. It is the only virus whose primary vectors are anopheline mosquitoes (Anopheles funestus and Anopheles gambiae).

Presentation

Common symptoms of infection with the virus are polyarthritis, rash and fever. Other symptoms include eye pain, chest pain, lymphadenitis and lethargy. No fatalities due to infection are known.

Epidemics

There have been two epidemics of O’nyong’nyong fever. The first occurred from 1959 to 1962, spreading from Uganda to Kenya, Tanzania, Zaire (Democratic Republic of the Congo), Malawi and Mozambique, and affecting over two million people. This was one of the largest arbovirus epidemics recorded. The first virus isolates were obtained during this outbreak from mosquitoes and human blood samples collected from Gulu in northern Uganda in 1959.

The second epidemic in 1996-1997 affected 400 people and was confined to Uganda. The 35-year hiatus between the two outbreaks and evidence of an outbreak in 1904-1906 in Uganda indicates a 30-50 year cycle for epidemics.

Strains

The ONNV (o'nyong-nyong virus) has at least three major subtypes, or strains, which genomic sequences are currently available on genome databases.

Cycle

It can involve a future or sylvatic cycle.[2]

References

  1. ^ Posey DL, O'rourke T, Roehrig JT, Lanciotti RS, Weinberg M, Maloney S (July 2005). "O'Nyong-nyong fever in West Africa". Am. J. Trop. Med. Hyg. 73 (1): 32. PMID 16014827. http://www.ajtmh.org/cgi/pmidlookup?view=long&pmid=16014827. 
  2. ^ Powers AM, Brault AC, Tesh RB, Weaver SC (February 2000). "Re-emergence of Chikungunya and O'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships". J. Gen. Virol. 81 (Pt 2): 471–9. PMID 10644846. http://vir.sgmjournals.org/cgi/pmidlookup?view=long&pmid=10644846. 

External links


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • O'Nyong-nyong-Virus — Klassifikation nach ICD 10 A92.1 O Nyong nyong Fieber …   Deutsch Wikipedia

  • O'nyong'nyong-Virus — Klassifikation nach ICD 10 A92.1 O Nyong nyong Fieber …   Deutsch Wikipedia

  • o'nyong-nyong virus — a species of togavirus of the genus Alphavirus, closely related to chikungunya virus; it causes o nyong nyong in East Africa and Senegal and is transmitted by anopheline mosquitoes …   Medical dictionary

  • Virus O'Nyong-Nyong — Le virus O nyong nyong est un arbovirus de la famille des Togaviridae et du genre des alphavirus, responsable d une arbovirose tropicale dénommée O nyong nyong. Il a été décrit pour la première fois en 1959 lors d une vaste épidémie en Afrique… …   Wikipédia en Français

  • Virus O'nyong'nyong — Le virus O nyong nyong est un arbovirus de la famille des Togaviridae et du genre des alphavirus, responsable d une arbovirose tropicale dénommée O nyong nyong. Il a été décrit pour la première fois en 1959 lors d une vaste épidémie en Afrique… …   Wikipédia en Français

  • Virus du Nil Occidental — Virus du Nil occidental …   Wikipédia en Français

  • Virus du nil occidental — Virus du Nil occidental …   Wikipédia en Français

  • Virus Marbourg — Virus Marburg Virus Marburg …   Wikipédia en Français

  • Virus de Marbourg — Virus Marburg Virus Marburg …   Wikipédia en Français

  • Virus de Marburg — Virus Marburg Virus Marburg …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”