Thiouracil

Thiouracil

Chembox new
ImageFile=Thiouracil.pngImageSize=120px
IUPACName=2-thioxo-1H-pyrimidin-4-one
OtherNames=
Section1= Chembox Identifiers
CASNo=141-90-2
PubChem=1269845
SMILES=C1=CNC(=S)NC1=O
MeSHName=Thiouracil

Section2= Chembox Properties
Formula=C4H4N2OS
MolarMass=128.153
Appearance=
Density=
MeltingPt=
BoilingPt=
Solubility=

Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

Thiouracil refers both to a specific molecule consisting of a sulfated uracil, and a family of molecules based upon that structure. The substance is a historically relevant antithyroid preparation; Astwood E.B. used it in 1943 as therapy of the Graves' disease for the first time. [http://books.google.com/books?id=LLoOUP-y54YC&pg=PA152&dq=parry+struma&hl=de&sig=bThK7levfOnNREWbw20F2Oddz7Q Gerabek W.: Enzyklopädie Medizingeschichte, S 152, 2005] ]

Reference


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • thiouracil — [thī΄ōyoor′ə sil] n. [ THIO + URACIL] a white, crystalline, bitter tasting powder, C4H4N2OS, used to reduce thyroid activity, and in treating angina pectoris …   English World dictionary

  • Thiouracil — Strukturformel Allgemeines Freiname Thiouracil Andere Namen …   Deutsch Wikipedia

  • thiouracil — thio·ura·cil .thī ō yu̇r ə .sil n a bitter crystalline compound C4H4N2OS that depresses the function of the thyroid gland * * * thio·ura·cil (thi″o uґrə sil) 1. a thiourea derivative that affects adversely the synthesis of the thyroid… …   Medical dictionary

  • thiouracil — noun depresses the function of the thyroid gland (Freq. 3) • Hypernyms: ↑organic compound * * * |thīō+ noun Etymology: International Scientific Vocabulary thi + uracil : a bitter crystalline compound C4H4N2OS that depresses the function of the… …   Useful english dictionary

  • thiouracil — noun Etymology: International Scientific Vocabulary Date: 1905 a bitter crystalline compound C4H4N2OS that depresses the function of the thyroid gland …   New Collegiate Dictionary

  • thiouracil — /thuy oh yoor euh sil/, n. Pharm. a white, slightly water soluble, bitter, crystalline powder C4H4N2OS, used chiefly in treating hyperthyroidism by reducing the activity of the thyroid gland. [1940 45; THIO + URACIL] * * * …   Universalium

  • thiouracil — noun Any of a class of heterocycles based on 2 thioxo 1H pyrimidin 4 one; the parent compound interferes with the synthesis of thyroxine and is used in the treatment of hyperthyroidism …   Wiktionary

  • thiouracil — n. chemical compound used as a medication for treating an overactive thyroid …   English contemporary dictionary

  • thiouracil — thio·uracil …   English syllables

  • 4-thiouracil — Uracil with S replacing O in position 4, isomeric with 2 thiouracil; a rare component of transfer RNAs …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”